After you take this medicine, wait at least 30 minutes before you eat or drink. Take this medicine only when you are in moderate withdrawal. This is the point when you feel like you want to use or inject to prevent more withdrawal symptoms. If you take it before you feel really sick, it can make your symptoms much worse.
Be sure to wait at least 1 hour in between doses. If this happens, call the clinic as your dose may be too strong. You should feel a little better or about the same after you take each dose. Take your first dose 2 mg and wait 1 hour. It will take 30 to 45 minutes for the medicine to start working. About 1 hour after your first dose, check to see how you feel.
If you feel better, about the same, or not much worse, take your second dose. Wait at least 1 hour after the fifth dose before you take your sixth dose. This is your final dose until your community clinic appointment.
Bring this handout to your next day follow-up appointment. To see this information online and learn more, visit MyHealth. Care instructions may be adapted by your healthcare provider. If you have questions about a medical condition or this instruction, talk with your doctor or appropriate healthcare provider.
It looks like your browser does not have JavaScript enabled. These forms of the two drugs are not all used to treat opioid dependence. During the maintenance phase, Suboxone is continued at a stable dose for a time ranging from several months to over a year. If you miss a dose during the maintenance phase, take it as soon as you remember. This means your body gets used to the drug and you need higher and higher doses to get the same effect. Drug tolerance has not been seen with Suboxone or with either of the drugs it contains buprenorphine or naloxone.
While taking Suboxone for opioid dependence, you may be required to do frequent drug tests for the use of opioids. There are different types of urine drug tests. Some of these tests, including the tests often used in those who take Suboxone for opioid dependence, can detect the presence of Suboxone and other opioid drugs. Most opioids can be detected within one to three days after use. However, Suboxone is long-lasting. It may be detected for longer periods of time. However, there are some home drug tests that do check for buprenorphine, one of the drugs in Suboxone.
This, of course, means a positive result for buprenorphine is a positive result for Suboxone. But if your symptoms are severe, call or go to the nearest emergency room right away. There are a few other drugs in addition to Suboxone that are used to treat opioid dependence.
Examples of these drugs include:. There are also other medications that contain buprenorphine plus naloxone, the ingredients in Suboxone. The brand names for these other medications are Bunavail and Zubsolv. You may wonder how Suboxone compares to other drugs used to treat opioid dependence. Below are comparisons between Suboxone and several medications. Subutex was a brand-name drug that contained buprenorphine, one of the ingredients in Suboxone. Brand-name Subutex is no longer available.
There are no brand-name forms of buprenorphine currently available for treating opioid dependence. The ones that are available are used to treat pain. Suboxone and buprenorphine, the generic form of Subutex, are both FDA-approved for treating opioid dependence. This includes both the induction and maintenance phases of treatment. During the induction phase, the drug decreases withdrawal symptoms while you stop or reduce opioid use.
During the maintenance phase, the drug keeps withdrawal symptoms and cravings in check as you complete your drug abuse or addiction treatment program. Suboxone comes as an oral film that can be used under your tongue sublingual or in your cheek buccal. Buprenorphine forms used for treating opioid dependence include an oral film, a sublingual tablet, and an implant for under the skin. In one study , Suboxone and buprenorphine were equally effective for reducing withdrawal symptoms during the induction phase the first phase of opioid dependence treatment.
In another study , starting induction treatment on day 1 with Suboxone was just as effective as starting with buprenorphine and then switching to Suboxone on day 3. The Substance Abuse and Mental Health Services Administration generally recommends Suboxone rather than buprenorphine for both the induction and maintenance phases of opioid dependence treatment.
However, Suboxone is only appropriate for induction in people who are dependent on short-acting opioids such as heroin, codeine, morphine, or oxycodone Oxycontin, Roxicodone. Buprenorphine, on the other hand, is recommended for people who are dependent on long-acting opioids such as methadone.
Suboxone and buprenorphine are very similar drugs and cause similar common and serious side effects. Suboxone is a brand-name drug. Generics are often less expensive than brand-name drugs. The Subutex brand-name product is no longer available. There are no brand-name forms of buprenorphine available that are used to treat opioid dependence. Buprenorphine and Suboxone cost about the same amount. However, the actual amount you pay will depend on your insurance.
Suboxone is a brand-name medication that contains two drugs: buprenorphine and naloxone. Methadone is a generic medication. Suboxone is FDA-approved to treat opioid dependence, including both the induction and maintenance treatment phases.
During the maintenance phase, the drug keeps withdrawal symptoms and cravings in check as you complete your drug abuse treatment program. Methadone is FDA-approved only for the maintenance phase of opioid dependence treatment. Methadone is also FDA-approved to treat moderate-to-severe pain. In addition, methadone is approved for treatment during opioid detoxification. Detoxification programs are generally short-term, inpatient treatment plans used to wean people off of drugs such as opioids or alcohol.
Suboxone comes as an oral film that can be used under your tongue sublingual or between your gums and your cheek buccal. Suboxone and methadone have been compared in clinical studies evaluating their use for treating opioid dependence.
In a study , Suboxone and methadone were found to be equally effective for reducing the use of opioids and keeping users in their treatment program. A study found that people taking Suboxone used opioids less compared to people taking methadone. However, the people taking methadone were more likely to stay in their treatment program. An analysis of several studies found that overall, Suboxone was more effective for reducing the use of opioid drugs, but methadone was more effective for keeping users in their treatment program.
Suboxone and methadone have some similar side effects, and some that differ. Below are examples of these side effects. This is the strongest warning that the FDA requires. A boxed warning alerts doctors and patients about drug effects that may be dangerous. Methadone usually costs less than brand-name or generic Suboxone. Both Suboxone and Zubsolv are brand-name medications that contain two drugs: buprenorphine and naloxone. Both Suboxone and Zubsolv are FDA-approved to treat opioid dependence, including the induction and maintenance phases of treatment.
Suboxone and Zubsolv contain the same drugs and are used in the same way to treat opioid dependence. The decision to use Suboxone or Zubsolv is based on personal preference for use of the sublingual film or tablet. Suboxone and Zubsolv are brand-name drugs. Zubsolv usually costs less than brand-name or generic Suboxone. Buprenorphine is classified as an opioid partial agonist-antagonist. This means it has some effects like opioid drugs, but it also blocks other opioid effects. Vivitrol is a brand-name medication that contains the drug naltrexone.
Naltrexone is an opioid antagonist, similar to the naloxone contained in Suboxone. This includes two phases of treatment: induction and maintenance. Vivitrol is also approved to treat opioid dependence. Suboxone and Vivitrol have been compared in clinical studies. A study found that Vivitrol and Suboxone were equally effective for reducing opioid and heroin use over 12 weeks. A study found that Suboxone was more effective for preventing relapse and was easier to use than Vivitrol.
Suboxone and Vivitrol have some similar side effects, and some that differ. Suboxone and Vivitrol are brand-name drugs. Generic versions often cost less than brand-name drugs. Vivitrol usually costs much more than brand-name or generic Suboxone. The actual amount you pay will depend on your insurance. Both Suboxone and Bunavail are brand-name medications that contains two drugs: buprenorphine and naloxone.
This includes both the induction phase and the maintenance phases of treatment. Suboxone is available as an oral film that can be used under your tongue sublingual or between your gums and your cheek buccal. Suboxone and Bunavail contain the same drugs and are used in the same way to treat opioid dependence.
The decision to use Suboxone or Bunavail is based on personal preferences for use of one product or the other. Suboxone and Bunavail are brand-name drugs. Bunavail usually costs less than brand-name or generic Suboxone. Naltrexone is a generic medication. Naltrexone is classified as an opioid antagonist, similar to the naloxone contained in Suboxone.
Naltrexone is also approved to treat opioid dependence. A clinical study found that Suboxone was more effective for reducing opioid use than naltrexone over 12 weeks.
Suboxone and naltrexone have some similar side effects, and some that differ. Naltrexone oral tablet is a generic drug. However, naltrexone also comes as extended-release injection. This form is only available as the brand-name drug Vivitrol [see above]. Naltrexone usually costs less than brand-name or generic Suboxone.
Suboxone can interact with several other medications. It can also interact with certain supplements as well as certain foods.
Different interactions can cause different effects. For instance, some can interfere with how well a drug works, while others can cause increased side effects. Below is a list of medications that can interact with Suboxone. This list does not contain all drugs that may interact with Suboxone. Before taking Suboxone, be sure to tell your doctor and pharmacist about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use.
Sharing this information can help you avoid potential interactions. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. Taking Suboxone with benzodiazepines can increase the risk of severe side effects such as severe sedation sleepiness , breathing problems, coma, and death. Taking these drugs with Suboxone can increase the risk of side effects.
Certain medications make an enzyme called cytochrome P 3A4 CYP3A4 more active and can increase how fast the body breaks down Suboxone. This can make Suboxone less effective. Taking Suboxone with medications that increase serotonin levels in your body might increase your risk of developing serotonin syndrome, a drug reaction that can be dangerous.
Anticholinergic drugs block the action of a chemical messenger called acetylcholine. Taking these drugs with Suboxone might increase the risk of side effects such as constipation and urinary retention. Xanax alprazolam is classified as a benzodiazepine. Taking Suboxone with benzodiazepines, including Xanax, can increase the risk of severe side effects. These include severe sedation sleepiness , breathing problems, coma, and death.
Taking tramadol Ultram, Conzip with Suboxone can increase the risk of side effects such as serotonin syndrome and decreased breathing. Suboxone may also make tramadol less effective for treating pain. There are no known interactions between Adderall amphetamine and dexamphetamine salts and Suboxone. Klonopin clonazepam is classified as a benzodiazepine.
Taking Suboxone with benzodiazepines, including Klonopin, can increase the risk of severe side effects. Suboxone and anesthesia used for surgery may interact and increase your risk of serious side effects. Before having surgery, talk with your doctor about your treatment with Suboxone. You may need to temporarily stop taking Suboxone.
Taking Suboxone with Ambien zolpidem can increase the risk of severe side effects. Taking codeine with Suboxone can increase the risk of side effects such as decreased breathing. Suboxone may also make codeine less effective for treating pain. Supplements that affect serotonin levels can increase your risk of developing serotonin syndrome.
Some herbs and supplements can cause sleepiness. Taking these along with Suboxone might increase your risk of excessive sleepiness. Examples of these supplements include:. Because of this, taking St. Drinking grapefruit juice while taking Suboxone might increase levels of Suboxone and increase your risk of side effects.
Suboxone is not swallowed. Instead, the film is placed under your tongue or between your gums and your cheek, where it will dissolve. However, you should not consume food or drink anything while the film is in your mouth. Research is limited on how these two drugs might affect a human pregnancy. Available studies have not found any major birth defects or other effects on the fetus when buprenorphine is used during pregnancy. In addition, women who take Suboxone while pregnant may need additional pain medication during labor and delivery.
This is because Suboxone blocks the effects of opioid medications, which may be used during labor and delivery to relieve pain. The American Society of Addiction Medicine recommends treatment with methadone rather than Suboxone for pregnant women who are opioid dependent. They also recommend buprenorphine alone not the Suboxone combination as an alternative choice. Untreated opioid dependence in pregnant women carries serious risks. They can help you determine the best treatment for you during your pregnancy.
These drugs are both thought to be safe to use during breastfeeding. If any of these potential side effects happen in your baby, contact your doctor right away. If your baby is not breathing or you cannot wake them up, call or emergency medical services. This means it has an accepted medical use, but may cause physical or psychological dependence and may be abused. To find out more, talk to your doctor or pharmacist.
No, Suboxone is not methadone. Suboxone may not be right for you if you have certain medical conditions. Examples of these conditions include:. Long-term use of Suboxone can lead to physical and psychological dependence. When Suboxone is dispensed, an expiration date is added to the label on the bottle.
This date is typically one year from the date the medication was dispensed. The purpose of these expiration dates is to guarantee the effectiveness of the medication during this time.
However, an FDA study showed that many medications may still be good beyond the expiration date listed on the bottle. How long the medication remains good can depend on many factors, including how and where the medication is stored.
If you have unused medication that has gone past its expiration date, talk to your pharmacist about whether you might still be able to use it.
Suboxone contains buprenorphine and naloxone. Buprenorphine is a partial agonist at the mu-opioid receptor and is an antagonist at the kappa-opioid receptor.
Stimulation of the mu receptor causes analgesia, respiratory depression, euphoria, and dependence. Due to its partial agonist effects, buprenorphine may reduce the pleasurable effects when mu-opioid receptor agonists are used.
Naloxone is a mu-opioid receptor antagonist. Naloxone is included in this formulation to prevent its use parenterally.
Naloxone has poor oral bioavailability and minimal amounts are absorbed when administered sublingually or buccally. Buprenorphine has better absorption when given sublingually compared to orally. The half-life is about 24 to 42 hours.
0コメント